Primal Health Databank: Study

Entry No:1044
Title:Exposure to vitamin D from fortified margarine during fetal life and later risk of pre-eclampsia: the D-tect Study
Author(s):Stougaard M, Damm P, et al
Reference:Public Health Nutr. 2017 Dec 20:1-11. doi: 10.1017/S1368980017003135. [Epub ahead of print]
Place of Study:Denmark
Abstract:Cancellation of the mandatory vitamin D fortification of margarine in 1985 created a societal experiment, with entire adjacent birth cohorts exposed or unexposed to extra vitamin D during fetal development. The Danish national medical health registries allowed the identification of pre-eclampsia cases later in life among all exposed and unexposed female individuals. Women born between June 1983 and August 1988, who gave birth to their first child at age 14·5-27·5 years (n 32 621)were included in the study The risk (95 % CI) for pre-eclampsia among women exposed v. unexposed to extra vitamin D from fortification during fetal development was 0·86 (0·76, 0·97). Exposure to extra vitamin D was associated with further reduced odds of pre-eclampsia (0·49 (0·34, 0·72)) among current smokers, but not among former smokers and non-smokers.
Keyword(s):pre-eclampsia, vitamin D
Discussion:No discussion mentioned for this entry
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