Primal Health Databank: Study
| Entry No: | 1024 |
| Title: | Retinopathy of Prematurity Is Associated with Increased Systolic Blood Pressure in Adults Who Were Born Preterm |
| Author(s): | Kistner A, Jacobson L, et al |
| Reference: | Neonatology. 2017;112(1):87-91. doi: 10.1159/000464243. Epub 2017 Apr 12. |
| Place of Study: | Sweden |
| Abstract: | The aim of this study was to evaluate the relationship between retinopathy of prematurity (ROP) and blood pressure (BP) and salivary cortisol levels during adulthood.
Sixty-nine subjects (mean age 22.6 years) were included. Subjects were adults who were: (a) ex-preterm infants with severe ROP (n = 22), born at gestational age (GA) <30 weeks with a birth weight (BW) <1,000 g, (b) ex-preterm infants with no/mild ROP (n = 21), born at GA <28 weeks with a BW <1,000 g, or (c) full-term controls (n = 26). Anthropometric data, office BP, ambulatory BP, and morning and evening salivary cortisol were analyzed.
As adults, ex-preterm infants with severe ROP had on average 7.4 mm Hg higher systolic office BP than those with no/mild ROP (p = 0.019) and controls (p = 0.007). A high cortisol level, tall height, and severe ROP were independent predictors of higher ambulatory systolic BP during adulthood in forward stepwise regression analysis, independent of GA.
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| Keyword(s): | Blood pressure, hypertension, prematurity, retinopathy of prematurity |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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