Primal Health Databank: Study
| Entry No: | 1011 |
| Title: | Psychotic illness after prenatal exposure to the 1953 Dutch Flood Disaster. |
| Author(s): | van der Graaf Y, et al |
| Reference: | Schizophr Res. 1999 Feb 15;35(3):243-5. |
| Place of Study: | Holland |
| Abstract: | The authors tested the hypothesis that maternal stress during pregnancy increases the risk of non-affective psychosis for the child. The concept of non-affective psychosis includes the ICD categories schizophrenic disorder, paranoid state and other non-organic psychosis. Data from the Dutch Psychiatric Registry were examined for an effect of the Flood Disaster of 1 February 1953. On this day, a gale caused a flood in the South-west of The Netherlands and 1835 people perished. This study concerned the 19 villages where mortality exceeded 0.25%. The risk of non-affective psychosis for the cohort born in the period February-October 1953 was compared to the risks for the cohorts born in the corresponding periods of the previous and subsequent 2 years. The relative risk of non-affective psychosis for those exposed during gestation was 1.8 [95% Confidence Interval (CI): 0.9-3.5]. |
| Keyword(s): | prenatal stress, schizophrenia |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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