Primal Health Databank: Study

Entry No:1008
Title: Maternal caffeine intake during pregnancy, early growth, and body fat distribution at school age.
Author(s):Jaddoe VW, et al
Reference:Obesity (Silver Spring). 2016 May;24(5):1170-7. doi: 10.1002/oby.21466. Epub 2016 Mar 26.
Place of Study:Netherlands
Abstract:In a population-based birth cohort among 7,857 mothers and their children, maternal caffeine intake during pregnancy was assessed by questionnaires. Growth characteristics were measured from birth onward. At 6 years, body fat and insulin levels were measured. Compared to children whose mothers consumed <2 units of caffeine per day during pregnancy (1 unit of caffeine is equivalent to 1 cup of coffee (90 mg caffeine)), those whose mothers consumed ≥6 units of caffeine per day tended to have a lower weight at birth, higher weight gain from birth to 6 years, and higher body mass index from 6 months to 6 years. Both children whose mothers consumed 4-5.9 and ≥6 units of caffeine per day during pregnancy tended to have a higher childhood body mass index and total body fat mass. Only children whose mothers consumed ≥6 units of caffeine per day had a higher android/gynoid fat mass ratio. CONCLUSIONS: These results suggest that high levels of maternal caffeine intake during pregnancy are associated with adverse offspring growth patterns and childhood body fat distribution.
Keyword(s):caffeine, coffee, fat distribution, Overweight
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