Primal Health Databank: Study
| Entry No: | 1007 |
| Title: | Association Between Cesarean Birth and Risk of Obesity in Offspring in Childhood, Adolescence, and Early Adulthood. |
| Author(s): | Yuan C, Gaskins AJ, et al |
| Reference: | JAMA Pediatr. 2016 Sep 6:e162385. doi: 10.1001/jamapediatrics.2016.2385. [Epub ahead of print] |
| Place of Study: | USA |
| Abstract: | This prospective cohort study was conducted from September 1, 1996, to December 31, 2012, among participants of the Growing Up Today Study, including 22 068 offspring born to 15 271 women, followed up via questionnaire from ages 9 to 14 through ages 20 to 28 years. Data analysis was conducted from October 10, 2015, to June 14, 2016.
:Of the 22 068 offspring (20 950 white; 9359 male and 12 709 female), 4921 individuals (22.3%) were born by cesarean delivery. The cumulative risk of obesity through the end of follow-up was 13% among all participants. The adjusted risk ratio for obesity among offspring delivered via cesarean birth vs those delivered via vaginal birth was 1.15 (95% CI, 1.06-1.26; P = .002). This association was stronger among women without known indications for cesarean delivery (adjusted risk ratio, 1.30; 95% CI, 1.09-1.54; P = .004). Offspring delivered via vaginal birth among women who had undergone a previous cesarean delivery had a 31% (95% CI, 17%-47%) lower risk of obesity compared with those born to women with repeated cesarean deliveries. In within-family analysis, individuals born by cesarean delivery had 64% (8%-148%) higher odds of obesity than did their siblings born via vaginal delivery.
CONCLUSIONS:
Cesarean birth was associated with offspring obesity after accounting for major confounding factors. |
| Keyword(s): | caesarean, cesarean, obesity |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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