Primal Health Databank: Study
| Entry No: | 0954 |
| Title: | Delivery by caesarean section and childhood cancer: a nationwide follow-up study in three countries. |
| Author(s): | Momen NC, Olsen J, et al |
| Reference: | BJOG. 2014 Oct;121(11):1343-50. doi: 10.1111/1471-0528.12667. Epub 2014 Feb 12. |
| Place of Study: | Denmark |
| Abstract: | POPULATION:
Children born in Denmark (1973-2007), Sweden (1973-2006) and Finland (randomly selected sample of 90%, 1987-2007; n = 7,029,843).
METHODS:
Exposure was delivery by caesarean section and the outcome was childhood cancer diagnosis. Follow-up started from birth and ended at the first of the following dates: cancer diagnosis, death, emigration, day before 15th birthday or end of follow-up. Cox regression was used to obtain hazard ratios.
MAIN OUTCOME MEASURES:
Childhood cancer diagnosis.
RESULTS:
A total of 882,907 (12.6%) children were delivered by caesarean section. Of these, 30.3% were elective (n = 267,603), 35.9% unplanned (n = 316,536) and 33.8% had no information on planning (n = 298,768). Altogether, 11,181 children received a cancer diagnosis. No evidence of an increased risk of childhood cancer was found for children born by caesarean section (hazard ratio, 1.05; 95% confidence interval, 0.99, 1.11). No association was found for any major type of childhood cancer, or when split by the type of caesarean section (elective/unplanned).
CONCLUSION:
The evidence does not suggest that caesarean section is a risk factor for the overall risk of childhood cancer and possibly not for subtypes of childhood cancer either. |
| Keyword(s): | caesarean, cancer in childhood, cesarean |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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