Primal Health Databank: Study

Entry No:0939
Title:Maternal diet during pregnancy and unilateral retinoblastoma.
Author(s):Lombardi C, Ganguly A, et al.
Reference:Cancer Causes Control. 2015 Mar;26(3):387-97. doi: 10.1007/s10552-014-0514-z. Epub 2014 Dec 27
Place of Study:USA
Abstract:This is a case-control study of 163 unilateral RB cases and 136 controls ascertained information on maternal diet during pregnancy using a standardized food frequency questionnaire. Logistic regression was used to assess the relation between retinoblastoma and food groups and dietary patterns. There was a negative association between retinoblastoma and intake of fruit [odds ratio (OR) 0.38, 95 % confidence interval (CI) 0.14-1.02]. Positive associations were seen with intake of cured meats (OR 5.07, 95 % CI 1.63-15.70) and fried foods (OR 4.89, 95 % CI 1.72-13.89). A food pattern of high fruits and vegetables and low fried food and sweets was negatively associated with disease (OR 0.75, 95 % CI 0.61-0.92). CONCLUSION: This study provides preliminary evidence that mothers who consume diets higher in fruit and lower in fried foods and cured meats during pregnancy may reduce the risk of unilateral retinoblastoma in their offspring.
Keyword(s):nutrition in pregnancy, retinoblastoma
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