Primal Health Databank: Study
| Entry No: | 0796 |
| Title: | Prevalence of hypospadias in grandsons of women exposed to diethylstilbestrol during pregnancy: a multigenerational national cohort study. |
| Author(s): | Kalfa N, Paris F, et al. |
| Reference: | Fertil Steril. 2011 Apr 1. [Epub ahead of print] |
| Place of Study: | France |
| Abstract: | Prenatal diethylstilbestrol (DES)-exposed mice have raised the suspicion of a transgenerational effect in the occurrence of genital malformation in males. This nationwide cohort study in collaboration with a French association of DES-exposed women studied 529 families and showed that a significant proportion of boys born to DES daughters exhibited hypospadias with no other molecular defects identified. |
| Keyword(s): | DES, hypospadias, transgenerational |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
Go Back | New Keyword Search