Primal Health Databank: Study
| Entry No: | 0787 |
| Title: | Thimerosal exposure |
| Author(s): | Geier DA, Young HA, Geier MR |
| Reference: | Indian J Med Res. 2010 Apr;131:500-7 |
| Place of Study: | USA |
| Abstract: | An association between premature puberty and exposure to Hg from thimerosal-containing vaccines (TCVs) was evaluated in computerized medical records within the Vaccine Safety Datalink (VSD).
A total of 278,624 subjects were identified in birth cohorts from 1990-1996. The birth cohort prevalence rates of medically diagnosed International Classification of Disease, 9(th) revision (ICD-9) premature puberty and control outcomes were calculated. Exposures to Hg from TCVs were calculated by birth cohort for specific exposure windows from birth-7 months and birth-13 months of age. Poisson regression analysis was used to model the association between the prevalence of outcomes and Hg doses from TCVs.
Significantly increased (P<0.0001) rate ratios were observed for premature puberty for a 100 microg difference in Hg exposure from TCVs in the birth-7 months (rate ratio=5.58) and birth-13 months (rate ratio=6.45) of age exposure windows. By contrast, none of the control outcomes had significantly increased rate ratios with Hg exposure from TCVs.
|
| Keyword(s): | puberty, thimerosal, vaccination |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
Go Back | New Keyword Search