Primal Health Databank: Study
| Entry No: | 0786 |
| Title: | Transgenerational response to nutrition, early life circumstances and longevity |
| Author(s): | Kaati G, Bygren LO, Pembrey ME, et al |
| Reference: | Eur J Hum Genet. 2007 Jul;15(7):784-90. Epub 2007 Apr 25. |
| Place of Study: | Sweden |
| Abstract: | Data from three random samples, comprising 271 probands and their 1626 parents and grandparents, left after exclusions because of missing data, were utilized. The availability of food during any given year was classified based on regional statistics. The ancestors' slow growth period was set at the ages of 8-12 years and the availability of food during these years classified as good, intermediate or poor. The probands' childhood circumstances were defined by the father's ownership of land, the number of siblings and order in the sibship, the death of parents and the parents' level of literacy. An earlier finding of a sex-specific influence from the ancestors' nutrition during the slow growth period, going from the paternal grandmother to the female proband and from the paternal grandfather to the male proband, was confirmed. In addition, a response from father to son emerged when childhood social circumstances of the son were accounted for. Early social circumstances influenced longevity for the male proband. Transgenerational responses to ancestors' nutrition prevailed as the main influence on longevity. |
| Keyword(s): | life expectancy, longevity, transgenerational |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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