Primal Health Databank: Study
| Entry No: | 0784 |
| Title: | Male-line transgenerational responses in humans |
| Author(s): | Pembrey ME |
| Reference: | Hum Fertil (Camb). 2010 Dec;13(4):268-71 |
| Place of Study: | Sweden |
| Abstract: | An ongoing collaboration between Umeå University, Sweden and the Avon Longitudinal Study of Parents and Childhood, Bristol University, UK has documented transgenerational correlations between food supply during the early life of the paternal grandparents and the grandchild's longevity, including associations with cardiovascular and diabetic deaths, and correlations between the onset of paternal smoking in mid-childhood and the body mass index of future sons. Whilst the mediating molecular mechanism(s) is unknown, the sex-specific transmission patterns and exposure-sensitive periods suggest a pre-evolved transgenerational response mechanism. |
| Keyword(s): | cardiovascular diseases, diabetes, life expectancy, longevity, transgenerational |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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