Primal Health Databank: Study
| Entry No: | 0737 |
| Title: | Fetal macrosomia and adolescence obesity: results from a longitudinal cohort study |
| Author(s): | Wang Y, Gao E, Wu J, et al. |
| Reference: | International Journal of Obesity (2009) 33, 923–928; doi:10.1038/ijo.2009.131 |
| Place of Study: | China |
| Abstract: | Between 1 October 2005 and 1 February 2007, a follow-up study of live-born infants born in 1993–1995 in Wuxi, a suburban area of Shanghai, was conducted. Subjects with birth weight > 4000 g were selected as the exposed. For each exposed subject, one subject with a birth weight of 2500–4000 g, matched by year of birth, sex of infant, and type of institute at birth, was chosen as non-exposed. Clinical data were collected by structured interview and physical examination. Obesity was defined as body mass index (weight (kg)/height (m2)) higher than the sex-age-specific criteria by the working group on obesity in China. Distribution of baseline characteristics and adolescent obesity rate between the exposed and non-exposed groups was compared.
A total of 1435 pairs of exposed and non-exposed subjects were included in the final analysis. No major difference in baseline characteristics (other than birth weight) was found between the exposed and non-exposed groups. Obesity rate was significantly higher in the exposed group (2.9%) than in the non-exposed group (1.6%). Adolescent obesity rates were 1.4, 1.9, 2.6, and 5.6%, respectively, in study subjects with a birth weight of 2500–3499, 3500–3999, 4000–4499, and 4500 g. The association between birth weight and adolescent obesity remained essentially the same when mother's demographic and anthropometric factors, breast feeding, and adolescent life-style factors were adjusted.
Conclusion: Compared with infants of normal birth weight, infants with birth weight >4000 g, especially those >4500 g, are at increased risk of adolescent obesity. |
| Keyword(s): | birthweight, macrosomia, obesity |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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