Primal Health Databank: Study
| Entry No: | 0723 |
| Title: | Psychiatric morbidity in adolescents and young adults born preterm: a Swedish national cohort study. |
| Author(s): | Lindstrom K, Lindblad F, Hjern A |
| Reference: | Pediatrics. 2009 Jan;123(1):e47-53 |
| Place of Study: | Sweden |
| Abstract: | A Swedish national cohort of 545628 individuals born in 1973-1979 was followed up in the national registers during 1987-2002. Multivariate Cox analysis of proportional hazards was used to estimate the hazard ratios of hospital admissions for psychiatric disorders and alcohol/illicit drug abuse. There was a stepwise increase in psychiatric hospital admissions with an increasing degree of preterm birth. A total of 5.2% of children born at 24 to 28 weeks' gestation and 3.5% born at 29 to 32 weeks' gestation had been hospitalized because of a psychiatric disorder. The hazard ratios for psychiatric disorders were 1.68 in the group of very preterm children (gestational weeks 24-32), 1.21 in the moderately preterm group (gestational weeks 33-36), and 1.08 in the early term group (gestational weeks 37-38) after adjustment for socioeconomic confounders. Moderately preterm and early term birth accounted for 85% of the risk attributed to preterm/early term birth. The effect of preterm birth was greater in households with low socioeconomic status. CONCLUSION: Preterm birth carries some risk for psychiatric disorders requiring hospitalization in adolescence and young adulthood (ages 8-29 years). Even if this risk increases with degree of preterm birth, most subjects are moderately preterm, a group in need of more attention in research and secondary prevention. |
| Keyword(s): | prematurity, psychiatric disease |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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