Primal Health Databank: Study
| Entry No: | 0678 |
| Title: | Effect of prolonged and exclusive breast feeding on risk of allergy and asthma: cluster randomised trial |
| Author(s): | Kramer MS, Matush L, Vanilovich I, Platt R, Bogdanovich N, Sevkovskaya Z, Dzikovich I, Shishko G, Mazer B |
| Reference: | BMJ. 2007 Oct 20;335(7624):815 |
| Place of Study: | Canada |
| Abstract: | 31 Belarussian maternity hospitals and their affiliated polyclinics were involved in the study. A total of 17,046 mother-infant pairs were enrolled, of whom 13,889 (81.5%) were followed up at age 6.5 years. The intervention was breastfeeding promotion modelled on the WHO/UNICEF baby friendly hospital initiative. The experimental intervention led to a large increase in exclusive breast feeding at 3 months (44.3% v 6.4%; P<0.001) and a significantly higher prevalence of any breast feeding at all ages up to and including 12 months. The experimental group had no reduction in risks of allergic symptoms and diagnoses or positive skin prick tests. In fact, after exclusion of six sites (three experimental and three control) with suspiciously high rates of positive skin prick tests, risks were significantly increased in the experimental group for four of the five antigens. These results do not support a protective effect of prolonged and exclusive breast feeding on asthma or allergy.
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| Keyword(s): | allergic disease, allergy, asthma, atopic diseases, breastfeeding |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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