Primal Health Databank: Study
| Entry No: | 0675 |
| Title: | Maternal Epilepsy and Offsprings' Adult Intelligence: A Population-Based Study from Norway |
| Author(s): | Oyen N, Vollset SE, Eide MG, Bjerkedal T, Skjærven R |
| Reference: | Epilepsia. 2007 Aug 31;48(9):1731-1738 |
| Place of Study: | Norway |
| Abstract: | In a population-based cohort study in Norway, information on maternal epilepsy reported to the Medical Birth Registry of Norway, 1967-1979 was linked to information on 18-19-year-old men's intellectual ability and anthropometric measures ascertained by the Norwegian Conscripts Service, 1984-1999. The standardized intelligence test (IQ score) was reported as single-digit standard scores with values from 1 to 9. No individual information on antiepileptic drug therapy was available. Mean IQ score was lower in 1,207 conscripts whose mothers had epilepsy reported on the birth notification form, as compared with 316,554 conscripts of mothers without epilepsy; 4.8 (standard deviation 1.8) versus 5.2(1.8), p < 0.001, respectively. This difference remained after adjustment for maternal education, maternal age, birth order, marital status, year of birth, and weight and length at birth. When comparing men with and without reported maternal epilepsy, the odds ratio of having an IQ score |
| Keyword(s): | epilepsy, intellectual development, IQ |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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