Primal Health Databank: Study

Entry No:0656
Title:Neonatal and 5-year outcomes after birth at 30-34 weeks of gestation
Author(s):Marret S, Ancel PY, Marpeau L, Marchand L, Pierrat V, Larroque B, Foix-L'Hélias L, Thiriez G, Fresson J, Alberge C, Rozé JC, Matis J, Bréart G, Kaminski M; Epipage Study Group
Reference:Obstet Gynecol. 2007 Jul;110(1):72-80
Place of Study:France
Abstract: In nine regions of France, all 2,020 stillbirths and live births at 30, 31, and 32 weeks in 1997 and all 457 births at 33 and 34 weeks in April and October 1997 were recorded. At 5 years of age, older gestational age was associated with significant decreases in rates of cerebral palsy (6.3% at 30 weeks and 0.7% at 34 weeks) and mild to severe cognitive impairments (35.3% at 30 weeks and 23.9% at 34 weeks). In singletons, preterm rupture of membranes or preterm labor carried an increased risk of cerebral palsy but not of cognitive impairment. These outcomes suggest that prolonging pregnancies beyond 34 weeks may be desirable whenever possible. Infants born at 30-34 weeks should be carefully monitored to ensure prompt detection and management of neurodevelopmental impairment.
Keyword(s):cerebral palsy, cognitive development, neurological development, prematurity
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