Primal Health Databank: Study
| Entry No: | 0641 |
| Title: | Prenatal alcohol exposure and gender differences in childhood mental health problems: a longitudinal population-based study |
| Author(s): | Sayal K, Heron J, Golding J, Emond A |
| Reference: | Pediatrics. 2007 Feb;119(2):e426-34 |
| Place of Study: | UK |
| Abstract: | This prospective, population-based study used data from the Avon Longitudinal Study of Parents and Children. The authors investigated the relationship between self-reports of the amount and frequency of alcohol use in the first trimester and the presence of clinically significant mental health (behavioral and emotional) problems at 47 and 81 months (parental report: n = 9086 and 8046, respectively) and at 93 to 108 months (teacher report: n = 5648). After controlling for a range of prenatal and postnatal factors, the consumption of <1 drink per week during the first trimester was independently associated with clinically significant mental health problems in girls at 47 months. This gender-specific association persisted at 81 months and was confirmed by later teacher ratings. CONCLUSIONS: Very low levels of alcohol consumption during early pregnancy may have a negative and persistent effect on mental health outcomes. Given the lack of a clear dose-response relationship and unexpected gender effects, these findings should be considered preliminary and need additional investigation.
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| Keyword(s): | alcohol in pregnancy, mental health |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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