Primal Health Databank: Study
| Entry No: | 0628 |
| Title: | Birth characteristics and subsequent risk for breast cancer in very young women |
| Author(s): | Innes K, Byers T, Schymura M |
| Reference: | Am J Epidemiol. 2000 Dec 15;152(12):1121-8 |
| Place of Study: | USA |
| Abstract: | This matched case-control study used linked New York State birth and tumor registry data to examine the association between birth characteristics and breast cancer risk among women aged 14-37 years. Cases were women diagnosed with breast cancer between 1978 and 1995 who were also born in New York after 1957 (n = 484). For each case, selected controls were the next six liveborn females with the same maternal county of residence. The authors found a J-shaped association between birth weight and breast cancer risk, and very high birth weight (> or =4,500 g) was associated with the greatest elevation in risk (adjusted odds ratio (OR) = 3.10, 95% confidence interval (CI): 1.18, 7.97). The association of maternal age with breast cancer risk was also J-shaped, with maternal age of more than 24 years showing a positive, linear association (adjusted OR = 1.94, 95% CI: 1.18, 3.18 for maternal age > or =35 vs. 20-24 years; p for trend = 0.02). In contrast, women born very preterm had a lower risk (adjusted OR = 0.11, 95% CI: 0.02, 0.79 for gestational age <33 vs. > or =37 weeks). |
| Keyword(s): | birth weight, breast cancer |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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