Primal Health Databank: Study
| Entry No: | 0579 |
| Title: | Preterm birth, low birth weight, and risk for esophageal adenocarcinoma |
| Author(s): | Kaijser M, Akre O, Cnattingius S, Ekbom A |
| Reference: | Gastroenterology. 2005 Mar;128(3):607-9 |
| Place of Study: | Sweden |
| Abstract: | In a cohort of 3364 individuals born preterm and/or small for gestational age between 1925 and 1949, the authors assessed the long-term risk for esophageal cancer. The standardized incidence rate ratio for esophageal adenocarcinoma was increased more than 7-fold in the cohort (standardized incidence rate ratio, 7.27; 95% confidence interval, 1.98-18.62), and a birth weight <2000 g was associated with a more than 11-fold increase in risk (standardized incidence rate ratio, 11.5; 95% confidence interval, 1.39-41.5). The associations may be explained by increased gastroesophageal reflux during infancy among infants born preterm and/or small for gestational age.
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| Keyword(s): | esophageal cancer, gastroesophageal reflux, low birthweight, prematurity |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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