Primal Health Databank: Study
| Entry No: | 0578 |
| Title: | Neurotropic viruses and cerebral palsy: population based case-control study |
| Author(s): | Gibson CS, MacLennan AH, Goldwater PN, Haan EA, Priest K, Dekker GA; South Australian Cerebral Palsy Research Group |
| Reference: | BMJ. 2006 Jan 14;332(7533):76-80 |
| Place of Study: | Australia |
| Abstract: | Newborn screening cards of 443 white case patients with cerebral palsy and 883 white controls were tested for viral nucleic acids from enteroviruses and herpes viruses by using polymerase chain reaction. Herpes group A viruses included herpes simplex viruses 1 and 2 (HSV-1 and HSV-2), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus 8 (HHV-8), and herpes group B viruses included varicella zoster virus (VZV) and human herpes viruses 6 and 7 (HHV-6 and HHV-7). The prevalence of viral nucleic acids in the control population was high: 39.8% of controls tested positive, and the prevalence was highest in preterm babies. The detection of herpes group B viral nucleic acids increased the risk of developing cerebral palsy (odds ratio 1.68, 95% confidence interval 1.09 to 2.59). |
| Keyword(s): | cerebral palsy, herpes |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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