Primal Health Databank: Study
| Entry No: | 0574 |
| Title: | Mode of Delivery Is Associated With Asthma and Allergy Occurrences in Children |
| Author(s): | Salam MT, Margolis HG, McConnell R, McGregor JA, Avol EL, Gilliland FD |
| Reference: | Ann Epidemiol. 2005 Oct 18 |
| Place of Study: | USA |
| Abstract: | A growing body of evidence indicates that perinatal factors modulate immune development and thereby may affect childhood asthma risk. In this study, the authors examined the associations between birth by cesarean section (C-section) and atopic disease occurrence in childhood. Subjects were born in California between 1975 and 1987 and were 8 to 17 years old during their enrollment in the Children's Health Study. The analysis was restricted to 3464 children born at or after 37 weeks of gestation with a birth weight of 2500 g or greater based on birth certificate data. Information about sociodemographic factors, reported physician-diagnosed asthma, and other atopic diseases was obtained by using a self-administered structured questionnaire. Logistic regression models were fitted to compute odds ratios (ORs) and 95% confidence intervals (CIs). Children born by C-section were at increased risk for asthma (OR, 1.33; 95% CI, 1.01-1.75), hay fever (OR, 1.57; 95% CI, 1.24-1.99), and allergy (OR, 1.26; 95% CI, 1.03-1.53) compared with those born vaginally. Risk associated with C-section was the same for children regardless of family history of asthma or allergy. |
| Keyword(s): | allergy, asthma, caesarean, cesarean, hay fever |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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