Primal Health Databank: Study

Entry No:0417
Title:Perinatal complications as predictors of infantile autism
Author(s):Wilkerson DS, Volpe AG, Dean RS, Titus JB, Kerr B, Hersh JH, Dean JC
Reference:Int J Neurosci 2002 Sep;112(9):1085-98
Place of Study:USA
Abstract:This study investigated the relationship between reported perinatal complications and autism. The biological mothers of 183 autistic children and 209 normals completed the Maternal Perinatal Scale (MPS), a maternal self-report that surveys complications of pregnancies and medical conditions of the mother. A discriminant analysis was performed to consider perinatal complications as predictors between the autistic and normal subjects. The results indicated significant differences on 3 of the 10 factors of the MPS, in particular, Gestational Age, Maternal Morphology, and Intrauterine Stress. When considered in an item by item fashion, 5 items were found to significantly predict group membership (prescriptions taken during pregnancy, length of labor, viral infection, abnormal presentation at delivery, and low birth weight). Finally, 3 maternal medical conditions were found to be highly significant and contribute to the separation between groups, including urinary infection, high temperatures, and depression.
Keyword(s):autism, autistic spectrum disorder, birth complications, head circumference, labor induction, labour induction, obstetric medication, preeclampsia, Rhesus-immunization
Discussion:Although there is an epidemic of labor induction that developed side by side with the epidemic of autism, it seems that the authors did not look at labor induction as a possible risk factor.
See Also:No related entries mentioned for this entry

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