Primal Health Databank: Study
| Entry No: | 0386 |
| Title: | Infant feeding and blood cholesterol: a study in adolescents and a systematic review |
| Author(s): | Owen CG, Whincup PH, Odoki K, Gilg JA, Cook DG |
| Reference: | Pediatrics 2002 Sep;110(3):597-608 |
| Place of Study: | UK |
| Abstract: | The objective of this study was to examine the influence of infant feeding method on serum total cholesterol (TC) and low-density lipoprotein (LDL) cholesterol. A cross-sectional study of 13- to 16-year-olds and a systematic review of studies on the effects of infant feeding on cholesterol in infancy (<1 year), childhood or adolescence (1-16 years), and adulthood (>/=17 years) were conducted using random effects models. Differences are presented as breastfed-bottle-fed. A total of 1532 individuals (92% white; 55% male; mean age: 15.1 years) in 10 British towns were studied, and 37 studies with 52 observations on TC (26 in infancy, 17 in childhood or adolescence, and 9 in adulthood; corresponding figures for LDL were 7, 4, and 6) were reviewed. Mean TC in childhood or adolescence (including the new study) was not related to infant feeding pattern (mean TC difference = 0.00; 95% confidence interval [CI]: -0.07 to 0.07 mmol/L). However, in infancy, mean TC was higher among those breastfed (mean TC difference = 0.64; 95% CI: 0.50-0.79 mmol/L), whereas in adults, mean TC was lower among those breastfed (mean TC difference = -0.18; 95% CI: -0.30 to -0.06 mmol/L). Patterns for LDL were similar to those for TC throughout. The conclusion of the authors is that breastfeeding is associated with increased mean TC and LDL levels in infancy but lower levels in adulthood/adult life. These results suggest that breastfeeding may have long-term benefits for cardiovascular health and may have implications for the content of formula feed milks.
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| Keyword(s): | breastfeeding, cholesterol |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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