Primal Health Databank: Study

Entry No:0379
Title:Type 2 diabetes mellitus in children: prenatal and early infancy risk factors among native canadians
Author(s):Type 2 diabetes mellitus in children: prenatal and early infancy risk factors among native canadians
Reference:Arch Pediatr Adolesc Med 2002 Jul;156(7):651-5
Place of Study:Canada
Abstract:BACKGROUND: Type 2 diabetes mellitus is increasingly being observed among children and youth, including the Native population of Canada. In this case-control study 46 patients younger than 18 years were recruited from the only clinical center for the treatment of diabetes serving the province of Manitoba, and 92 age- and sex-matched controls were recruited from a pediatric ambulatory clinic serving a large Native population in Winnipeg, Manitoba. Information on exposure to prenatal and early infancy risk factors was obtained through questionnaires administered by a Native nurse-interviewer. Multiple logistic regression modeling identified preexisting diabetes (odds ratio [OR], 14.4; 95% confidence interval [CI], 2.86-72.5), gestational diabetes (OR, 4.40; 95% CI, 1.38-14.1), and breastfeeding for at least 12 months (OR, 0.24; 95% CI, 0.13-0.99) as significant independent predictors of diabetic status. Other factors, such as low (<2500 g) and high (>4000 g) birth weight and maternal obesity, were also associated with diabetes in this population, but the elevated risks were not statistically significant. The authors conclude that breastfeeding reduces the risk of type 2 diabetes among Native Canadian children and should be promoted as a potential intervention to control the disease.
Keyword(s):breastfeeding, diabetes, diabetes type 2
Discussion:No discussion mentioned for this entry
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