Primal Health Databank: Study
| Entry No: | 0347 |
| Title: | Preterm birth, vascular function, and risk factors for atherosclerosis |
| Author(s): | Atul Singhal, Mia Kattenhorn, Tim J Cole, John Deanfield, Alan Lucas |
| Reference: | Lancet 2001; 358: 1159-60 |
| Place of Study: | UK |
| Abstract: | Low birthweight may predispose to the development of atherosclerosis later in life. The authors have tested the hypothesis that low birthweight as a result of preterm birth is associated with reduced flow-mediated endothelial-dependent vasodilation (FMD), which is an early stage in the development of atherosclerosis. Mean FMD in adolescents born preterm who had a low birthweight did not differ from that for controls born at term (0·225 mm vs 0·220 mm, SD 0·1 for both means, p=0·78). Such findings indicate that low birthweight attributable to prematurity does not increase the risk of vascular disease later in life.
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| Keyword(s): | atherosclerosis, birthweight, prematurity |
| Discussion: | No discussion mentioned for this entry |
| See Also: | No related entries mentioned for this entry |
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