Primal Health Databank: Study
| Entry No: | 0248 |
| Title: | Reduced fetal growth rate and increased risk of death from ischaemic heart disease: cohort study of 15,000 Swedish men and women born 1915-29 |
| Author(s): | Leon DA, Lithell HO, et al. |
| Reference: | BMJ 1998; 317: |
| Place of Study: | Sweden |
| Abstract: | All 14,611 babies born at the Uppsala Academic Hospital during 1915-29 were followed up until the end of 1995. The mortality from ischaemic heart disease and other causes was evaluated. There was an inverse correlation between birth weight and the risk of ischaemic heart disease. This was statistically significant for men, but not for women. It appeared that it is birth weight for gestational age rather than birth weight per se that is important. For all other causes of death, except respiratory disease, mortality decreased as birth weight increased. The largest effects were for ischaemic heart disease and cerebrovascular disease, although only ischaemic heart disease among men showed a significant association. |
| Keyword(s): | birth weight, coronary heart disease, fetal growth, mortality rates |
| Discussion: | This is one of the most convincing studies demonstrating a real association between fetal growth and mortality from ischaemic heart disease. |
| See Also: | No related entries mentioned for this entry |
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