Primal Health Databank: Study
| Entry No: | 0112 |
| Title: | Case-control study of antenatal and intrapartum risk factors for cerebral palsy in very preterm singleton babies |
| Author(s): | Murphy DJ, Sellers S, et al., Hsieh CC, Lan SJ., Adami HO, Trichopoulos D. |
| Reference: | Lancet 1995; 346: 1449-54 |
| Place of Study: | Oxford, England |
| Abstract: | This study involves 59 very preterm babies who developed cerebral palsy and were compared with 334 randomly selected controls. The frequency of cerebral palsy decreased with increased gestational age and birth weight. One of the most interesting findings is that pre-eclampsia was associated with a reduced risk of cerebral palsy. |
| Keyword(s): | birth weight, cerebral palsy, pre-eclampsia, preeclampsia, toxemia |
| Discussion: | See entry 0111. Such findings support our point of view that brain development is a priority amongst humans. The occurrence of pre-eclampsia implies that fetal brain development has been such an unconditional priority that there has been a transfer of nutrients (in particular DHA) in excess of the maternal safety limit. The consequence of preserving the needs of the developing brain at any price may be a life threatening disease ... but the risk of cerebral palsy is reduced. Let us notice that in this study none of the mothers had been treated by magnesium sulphate (the administration of magnesium sulphate by itself may reduce the risk of cerebral palsy). |
| See Also: | 0111 |
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