Primal Health Databank: Study
| Entry No: | 0067 |
| Title: | Crohn's disease after in utero measles virus exposure |
| Author(s): | Ekbom A, Daszak P, et al. |
| Reference: | Lancet 1996; 348: 515-17 |
| Place of Study: | Sweden |
| Abstract: | Maternity charts for all 25,000 deliveries at University Hospital Uppsala between 1940-49 were reviewed: four cases of measles infection of the mother during pregnancy were identified. The children and two of their mothers were interviewed and case records reviewed. Three offspring had undergone multiple intestinal resections for Crohn's disease. Measles virus antigen was detected in the intestinal lesions in all children with Crohn's disease. |
| Keyword(s): | Crohn's disease, measles |
| Discussion: | Such data suggest that exposure to measles virus in utero is a risk factor for Crohn's disease. |
| See Also: | No related entries mentioned for this entry |
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